Juvederm® Ultra 2 with numbing agent is an injectable filler, which is used to treat superficial to moderat facial lines and skin depressions, usually those around the lips and eyes. Juvederm® Ultra 2 contains HA, which is a natural substance found inside the human body. Its key property is to keep the skin hydrated whilst adding plumpness. The product contains a numbing agent to ensure a more comfortable injection.